Massive Hepatomegaly - Can it be acute lymphoid leukemia?

Acute tubular necrosis: can it be prevented?

Acute promyelocytic leukemia can be treated successfully without cytotoxic chemotherapy.

In their scholarly article, Dr. Park and Dr. Tallman review the important clinical trials for treating patients with APL reported over the last two decades and argue the case for further reduction and perhaps elimination of conventional cytotoxic chemotherapy in the frontline treatment of this disease.[1] Treatment of APL has evolved during the last several decades following the demonstration t...

MicroRNA profiling can classify acute leukemias of ambiguous lineage as either acute myeloid leukemia or acute lymphoid leukemia.

PURPOSE Classification of acute leukemia is based on the commitment of leukemic cells to the myeloid or the lymphoid lineage. However, a small percentage of acute leukemia cases lack straightforward immunophenotypical lineage commitment. These leukemias of ambiguous lineage represent a heterogeneous category of acute leukemia that cannot be classified as either acute myeloid leukemia (AML) or a...

MicroRNA profiling can classify acute leukemias of ambiguous 1 lineage as either acute myeloid leukemia or acute lymphoid 2 leukemia

MicroRNA profiling can classify acute leukemias of ambiguous 1 lineage as either acute myeloid leukemia or acute lymphoid 2 leukemia. 3 4 David C. de Leeuw, Willemijn van den Ancker, Fedor Denkers, Renée X. de Menezes, 5 Theresia M. Westers , Gert J. Ossenkoppele , Arjan A. van de Loosdrecht 1 and Linda 6 Smit . 7 8 Authors’ Affiliation: 9 1 Department of Hematology, VU University Medical Cente...

Acute massive myelofibrosis with acute lymphoblastic leukemia.

Acute myelofibrosis is characterized by pancytopenia of sudden onset, megakaryocytic hyperplasia, extensive bone marrow fibrosis, and the absence of organomegaly. Acute myelofibrosis in patients with acute lymphoblastic leukemia is extremely rare. We report a 4-year-old boy who was diagnosed as having acute massive myelofibrosis and acute lymphoblastic leukemia. Performing bone marrow aspiratio...